Should middle age guys take supplements to help reach their fitness goals? Well, that depends on what your goals are. If you’re just trying to get a little leaner and fitter, then you probably don’t need supplements. Getting older is tough, though. I recently turned 43 and I can’t do what I used to do in my 30s. Part of it is because I haven’t worked out regularly for about 5 years. However, my endurance had really deteriorated over the last few years. It was never that great previously due to my mitochondrial disorder and now it’s really difficult to exercise. Would nutritional supplements help?